| Saruparib in Combination With Physician’s Choice of ARPI in Patients With mHSPC Previously Treated With Docetaxel or 177Lu-PSMA Therapy Without Disease Progression and PSA ≥ 0.2 ng/mL (EvoPAR-PR05) (EvoPAR-PR05) |
Nature et Objective
A Randomized, Double-Blind, Placebo-Controlled, 2-Cohort, phase III study. The primary objective of this study is to measure efficacy of saruparib + physician’s choice of ARPI compared with placebo + ARPI in men with metastatic hormone-sensitive prostate cancer (mHSPC) who have previously received docetaxel chemotherapy or a prostate-specific membrane antigen (PSMA)-directed lutetium-177 radioligand therapy with no evidence of disease progression and PSA ≥ 0.2 ng/mL.
Stade de la Maladie: Métastatique
Organe: Prostate
Maladie: Cancer de la prostate