TACT-Safety
The Effect of Tranexamic Acid on Oncologic Outcomes: The TACT-SAFETY study – Retrospective study Nature et objective :We hypothesize that TXA during cancer surgery is safe and does not increase the risk of cancer recurrence. To address this hypothesis, we aim to extend the follow up of TACT patients beyond the peri-operative period to assess the […]
V940-005
Phase 2, Randomized, Double-blind, Placebo- and Active-comparator controlled Clinical Study of Adjuvant V940 (mRNA-4157) Plus Pembrolizumab Versus Adjuvant Placebo Plus Pembrolizumab in Participants With High-risk Muscle-invasive Urothelial Carcinoma Post-radical Resection Nature and objective :The purpose of this study is to assess the safety and efficacy of V940 in combination with pembrolizumab (MK-3475) compared to pembrolizumab alone […]
CAAA617B12203 (PSMACare)
An International Prospective Open-label, Multi-center, Randomized, non-comparative Phase II Study of Lutetium [177Lu] vipivotide tetraxetan (AAA617) alone and Lutetium [177Lu] vipivotide tetraxetan (AAA617) in combination with Androgen Receptor Pathway Inhibitors in patients with PSMA PET scan positive Castration-Resistant Prostate Cancer Nature and objective :The purpose of this study is to evaluate the efficacy and safety of […]
SUMMIT
Real-world clinical study evaluating the performance of the Optilume® BPH catheter system in men with symptomatic benign prostatic hyperplasia (SUMMIT) Nature et objective :Benign prostatic hypertrophy (BPH) is a benign enlargement of the prostate, common in older men and sometimes in younger men as young as 31 years old. Symptoms include urinary problems such as delayed […]
BicaBCa
A Phase II randomized trial of bicalutamide among patients receiving intravesical induction BCG for non-muscle invasive bladder cancer Nature and objective :Bladder cancer, the second most common urological cancer after prostate cancer, is often treated by intravesical instillation of bacillus Calmette-Guérin (BCG). However, a significant percentage of patients experience relapses or disease progression. This study aims […]
